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First Human-Animal Embryos in U.K. Bring Opposition

Andrea Gerlin
Bloomberg
Wednesday, April 2, 2008

The creation of the U.K.'s first part-human, part-animal embryos may increase pressure on Parliament for tougher regulations on stem cell research.

Lyle Armstrong and colleagues at Newcastle University made embryos using human cells and a cow egg, the college said yesterday in a statement on its Web site. Debate in the U.K. over the so-called hybrid embryos increased after Catholic leaders, in Easter sermons, attacked the technique used for making stem cells. Cardinal Keith O'Brien of Edinburgh said creating such embryos were ``experiments of Frankenstein proportion.''

Parliament is discussing changes to a 1990 law that governs stem cell research, including the hybrid work. U.K. scientists, who can conduct research U.S. President George W. Bush restricted in 2001, are concerned that they'll fall behind other countries if legislation before Parliament is defeated. Chinese and U.S. academics already have produced stem cells extracted from part- human, part-animal embryos.

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The new hybrids ``will open the door to a better understanding of disease processes without having to use precious human eggs,'' John Burn, head of the Institute of Human Genetics at Newcastle University, said in the statement. ``Cells grown using animal eggs cannot be used to treat patients on safety grounds but they will help bring nearer the day when new stem cell therapies are available.''

Armstrong presented preliminary data last month at a lecture in Israel, and is working to verify the data, the university said yesterday.

Lobbying, Debates

In response to the criticism from religious leaders, medical organizations are organizing supporters to lobby legislators. O'Brien has agreed to a Catholic lawmaker's request that he meet researchers who want to use hybrid embryos. Cardinal Cormac Murphy-O'Connor, the leader of Catholics in England and Wales, wants a national bioethics panel established.

Two days after O'Brien's Easter sermon, Prime Minister Gordon Brown agreed to allow lawmakers in his Labour party and Cabinet ministers to vote based on their consciences as opposed to their party's position when they're polled in May or June. Three of Brown's Cabinet ministers are Catholic and may have resigned rather than support the bill.

Among the proposed changes to the 1990 Human Fertilization and Embryology Act is a provision allowing researchers to generate stem cells from hybrid embryos.

Full article here.

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